HPS6 antibody (Internal Region)

Catalog No. ABIN374513

Product Details anti-HPS6 Antibody

Target: HPS6 (Hermansky-Pudlak Syndrome 6 (HPS6))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This HPS6 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody reacts to HPS6.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Porcine, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence LRTELRDYRGLEC, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/32000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-HPS6 antibody (ABIN374513)

Stephen, Yokoyama, Tolman, OBrien, Nicoli, Brooks, Huryn, Titus, Adams, Chen, Gahl, Gochuico, Malicdan: "Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5." in: PLoS ONE, Vol. 12, Issue 3, pp. e0173682, (2017) (PubMed).

Target Details for HPS6

Target: HPS6 (Hermansky-Pudlak Syndrome 6 (HPS6))

Alternative Name: HPS6 (HPS6 Products)

Synonyms: RP11-302K17.1 antibody, 5330434M19Rik antibody, BLOC2 antibody, ru antibody, Hsp6 antibody, HPS6, biogenesis of lysosomal organelles complex 2 subunit 3 antibody, HPS6 antibody, hps6 antibody, Hps6 antibody

Background: HPS6 has an intronless gene and may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. HPS6 interacts with Hermansky-Pudlak syndrome 5 protein. Mutations in HPS6 gene are associated with Hermansky-Pudlak syndrome type 6.Synonyms: HPS-6, Hermansky-Pudlak syndrome 6 protein, Ru, Ruby-eye protein homolog

Gene ID: 79803

NCBI Accession: NP_079023

UniProt: Q86YV9