EPB41L3 antibody (C-Term)

Catalog No. ABIN374633

The Goat Polyclonal anti-EPB41L3 antibody is suitable to detect EPB41L3 in samples from Human, Mouse, Rat and Dog. It has been validated for WB.

Quick Overview for EPB41L3 antibody (C-Term) (ABIN374633)

Target: EPB41L3 (Erythrocyte Membrane Protein Band 4.1 Like 3 (EPB41L3))

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This EPB41L3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EPB41L3 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to EPB41L3.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-HKETEITPEDGED, from the C Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/2000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for EPB41L3

Target: EPB41L3 (Erythrocyte Membrane Protein Band 4.1 Like 3 (EPB41L3))

Alternative Name: EPB41L3

Background: EPB41L3 is an actin-binding protein originally identified as a molecule whose expression is down-regulated in lung adenocarcinoma. EPB41L3 is a member of the protein 4.1 superfamily, which encompasses structural proteins that play important roles in membrane processes via interactions with actin, spectrin, and the cytoplasmic domains of integral membrane proteins. The gene for EPB41L3 is thought to function as a tumor suppressor and localizes within chromosomal region 18p11.3, which is affected by loss of heterozygosity (LOH) in various adult tumors.Synonyms: 4.1B, Band 4.1-like protein 3, DAL-1, DAL1, Differentially expressed in adenocarcinoma of the lung protein 1, KIAA0987

Gene ID: 23136

NCBI Accession: NP_036439

UniProt: Q9Y2J2

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location