ADRA2A antibody (Internal Region)

Catalog No. ABIN374651

The Goat Polyclonal anti-ADRA2A antibody is suitable to detect ADRA2A in samples from Human, Rat, Mouse and Dog. It has been validated for IF and EIA.

Quick Overview for ADRA2A antibody (Internal Region) (ABIN374651)

Target: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Reactivity: Human, Rat, Mouse, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This ADRA2A antibody is un-conjugated

Application: Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-ADRA2A Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to Alpha-2A adrenergic receptor.

Cross-Reactivity (Details): Species reactivity (expected):Human, Rat, Canine.
Species reactivity (tested):Mouse.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-TERRPNGLGPERS, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/32000. Western Blot. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ADRA2A

Target: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Alternative Name: alpha-2A Adrenergic Receptor

Background: Alpha 2 adrenergic receptors mediate the catecholamine induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.Synonyms: ADRA2A, ADRA2R, ADRAR, Alpha-2A adrenoceptor, Alpha-2A adrenoreceptor

Gene ID: 150, 9606

UniProt: P08913

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity