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AKR1C4 antibody (N-Term)

AKR1C4 Reactivity: Human WB, IHC (p) Host: Goat Polyclonal unconjugated
Catalog No. ABIN374680
  • Target See all AKR1C4 Antibodies
    AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
    Binding Specificity
    • 8
    • 8
    • 7
    • 7
    • 1
    • 1
    N-Term
    Reactivity
    • 36
    • 9
    • 3
    Human
    Host
    • 29
    • 5
    • 1
    • 1
    Goat
    Clonality
    • 34
    • 2
    Polyclonal
    Conjugate
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKR1C4 antibody is un-conjugated
    Application
    • 28
    • 19
    • 7
    • 4
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody reacts to AKR1C4 / DDH4. This antibody may cross-react with AKR1C1.
    Purification
    Affinity chromatography
    Immunogen
    Peptide with sequence DPKYQRVELNDGH-C, from the N Terminus of the protein sequence
    Top Product
    Discover our top product AKR1C4 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/4000. Western Blot: 0.1 - 0.3 μg/mL. Immunohistochemistry on paraffin sections: 2 - 4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
    Alternative Name
    AKR1C4 (AKR1C4 Products)
    Synonyms
    3-alpha-HSD antibody, C11 antibody, CDR antibody, CHDR antibody, DD-4 antibody, DD4 antibody, HAKRA antibody, aldo-keto reductase family 1 member C4 antibody, AKR1C4 antibody
    Background
    HSD3a catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3alpha,17beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity.Synonyms: 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, Aldo-keto reductase family 1 member C4, CDR, CHDR, Chlordecone reductase, DD-4, DD4, Dihydrodiol dehydrogenase 4, HAKRA
    Gene ID
    1109, 9606
    UniProt
    P17516
    Pathways
    Steroid Hormone Biosynthesis
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