VDAC2 antibody (Internal Region)

Catalog No. ABIN374727

Product Details anti-VDAC2 Antibody

Target: VDAC2 (Voltage-Dependent Anion Channel 2 (VDAC2))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This VDAC2 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody recognizes VDAC2.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence C-DSAKSKLTRNN, from the internal region of the protein sequence according to NP_003366.2.

Application Details

Application Notes: Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for VDAC2

Target: VDAC2 (Voltage-Dependent Anion Channel 2 (VDAC2))

Alternative Name: VDAC2 (VDAC2 Products)

Synonyms: POR antibody, Vdac6 antibody, mVDAC2 antibody, mVDAC6 antibody, wu:fa01a08 antibody, wu:fa98a10 antibody, wu:fb50g11 antibody, zgc:55795 antibody, zgc:77621 antibody, vdac2 antibody, VDAC2 antibody, ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 2 antibody, ATVDAC2 antibody, K9I9.6 antibody, K9I9_6 antibody, voltage dependent anion channel 2 antibody, voltage dependent anion channel 2 antibody, voltage-dependent anion channel 2 antibody, voltage-dependent anion channel 2 S homeolog antibody, VDAC2 antibody, Vdac2 antibody, vdac2 antibody, vdac2.S antibody

Background: VDAC2 forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. VDAC2 interacts with hexokinases. It is present in the outer mitochondrial membrane. There are 4 isoforms as result of alternative splicing. It consists mainly of membrane spanning sided beta sheets, and belongs to the eukaryotic mitochondrial porin family.Synonyms: Outer mitochondrial membrane protein porin 2, VDAC-2, Voltage-dependent anion-selective channel protein 2

Gene ID: 7417, 9606

UniProt: P45880