Phosphatidylethanolamine Binding Protein 1 (PEBP1) (Internal Region) antibody

Details for Product No. ABIN374748
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms HCNP, HCNPpp, PBP, PEBP, PEBP-1, RKIP, Pbp, Pbp1, Pbpr, Rkip, BcDNA:LP12095, CG18594, Dmel\\CG18594, PEBP1, T2, pbp, hcnp, pebp, rkip
Epitope
Internal Region
(17), (13), (13), (9), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(109), (47), (47), (24), (18), (17), (13), (1), (1), (1), (1), (1)
Host
Goat
(93), (18), (14)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(98), (75), (27), (26), (19), (4), (4), (2)
Pubmed 1 reference available
Catalog no. ABIN374748
Quantity 0.1 mg
Price
357.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Peptide with sequence C-DPDAPSRKDPKYRE, from the internal region of the protein sequence according to NP_002558.1. Genename: PEBP1
Specificity This antibody reacts to PEBP1/RKIP. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Rat and Canine.
Purification Ammonium sulphate precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
Alternative Name PEBP1 / RKIP
Background PBP, also known as RKIP (RAF kinase inhibitor protein), binds ATP, opioids and phosphatidylethanolamine. PBP is able to regulate Aurora kinase B expression and the spindle checkpoint through interaction with the RAF1/MEK/ERK cascade. PBP is able to bind to RAF1 and MEK and competitively disrupt the interaction between these proteins. PBP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. It increases the production of choline acetyltransferase but not acetylcholinesterase. PBP has been implicated as a suppressor of metastasis.
Alternate names: HCNPpp, PBP, PEBP, PEBP-1, Phosphatidylethanolamine-binding protein 1, Prostatic- binding protein, Raf kinase inhibitor protein
Gene ID 5037
NCBI Accession NP_002558.1
UniProt P30086
Application Notes Peptide ELISA: Detection Limit: 1/128000. Western blot: 0.01-0.03 µg/ml. Approx 21kDa band observed in Human Prostate lysates(calculated MW of 21.1kDa according to NP_002558.1). Immunohistochemistry: 2-5 µg/ml. In paraffin embedded Adrenal Gland shows strongstinaing of secretory cells. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris buffered saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (Internal Region) antibody anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (Internal Region) antibody
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (Internal Region) antibody (2) anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (Internal Region) antibody (Image 2)
Background publications Yeung, Seitz, Li et al.: "Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP." in: Nature, Vol. 401, Issue 6749, pp. 173-7, 1999 (PubMed).

Hosts (93), (18), (14)
Reactivities (109), (47), (47), (24), (18), (17), (13), (1), (1), (1), (1), (1)
Applications (98), (75), (27), (26), (19), (4), (4), (2)
Conjugates (4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (17), (13), (13), (9), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
back to top