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Details for Product No. ABIN374802

Glucose-6-Phosphate Dehydrogenase (G6PD) (Internal Region) antibody

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Antigen
Synonyms G6PD1, G6pdx, g6pd, G6PD, G6pd, Dsim\\\\G6pd, Dsim\\\\G6pdh, G-6PD, dsim_GLEANR_8868, Dsim\\\\GD24877, GD24877, Zw, g6pdh, g6pd2, fj78b06, wu:fj78b06, si:dkey-90a13.8, BA3433, PSPTO1300, PSPTO3121
Epitope
»Alternatives Internal Region
Reactivity
»Alternatives Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN374802
Quantity 0.1 mg
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Peptide from the internal region of the protein sequence according to NP_000393.4 , NP_001035810.1 Genename: G6PD
Sequence C-KPASTNSDDVRDEK
Specificity This antibody detetcs G6PD. It is expected to recognise both reported isoforms (NP_000393.4 and NP_001035810.1). Species Reactivity: Tested: Human Expected from sequence similarity: Mouse, Rat, Dog
Purification Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
Alternative Name G6PD
Background Glucose 6 Phosphate Dehydrogenase (G6PD) produces pentose sugars for nucleic acid synthesis and is the main producer of NADPH reducing power. Catalytic activity: D glucose 6 phosphate + NADP(+) = D glucono 1,5 lactone 6 phosphate + NADPH. Defects in G6PD are the cause of chronic non spherocytic haemolytic anemia (CNSHA). G6PD deficiency is the most common human enzyme deficiency, one benefit of having G6PD deficiency is that it confers a resistance to malaria.
Alternate names: Glucose-6-P-Dehydrogenase, Glucose-6-phosphate 1-dehydrogenase
Gene ID 2539
NCBI Accession 9606
UniProt P11413
Application Notes Peptide ELISA: antibody detection limit dilution 1: 8000. Western blot: 0.1-0.3µg/ml. Approx 60kDa band observed in Human Placenta lysates(calculated MW of 62.5kDa according to NP_000393.4 and 59.3kDa according toNP_001035810.1). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
Expiry Date 12 months
Background publications Guindo, Fairhurst, Doumbo et al.: "X-linked G6PD deficiency protects hemizygous males but not heterozygous females against severe malaria." in: PLoS medicine, Vol. 4, Issue 3, pp. e66, 2007 (PubMed).

Alternatives for antigen "Glucose-6-Phosphate Dehydrogenase (G6PD)", type "Antibodies"
Hosts (93), (37), (24)
Reactivities (102), (47), (43), (28), (26), (24), (12), (12), (9), (6), (3), (1), (1)
Applications (122), (96), (30), (29), (23), (20), (16), (14), (11), (11), (7), (5), (5), (4), (2), (1), (1)
Conjugates (22), (8), (4), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Epitopes (9), (6), (5), (5), (4), (3), (2), (1), (1), (1), (1), (1), (1)
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