Glucose-6-Phosphate Dehydrogenase (G6PD) (Internal Region) antibody

Details for Product No. ABIN374802
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Antigen
Synonyms
g6pd, G6pd, Dsim\\\\G6pd, Dsim\\\\G6pdh, G-6PD, G6PD, dsim_GLEANR_8868, Dsim\\\\GD24877, GD24877, Zw, g6pdh, g6pd2, fj78b06, wu:fj78b06, si:dkey-90a13.8, BA3433, PSPTO1300, PSPTO3121, G6PD1, G6pdx, G6 ... show more
g6pd, G6pd, Dsim\\\\G6pd, Dsim\\\\G6pdh, G-6PD, G6PD, dsim_GLEANR_8868, Dsim\\\\GD24877, GD24877, Zw, g6pdh, g6pd2, fj78b06, wu:fj78b06, si:dkey-90a13.8, BA3433, PSPTO1300, PSPTO3121, G6PD1, G6pdx, G6pdx-ps1, Gpd-2, Gpd2, CORTRD1, G6PDH, GDH show less
Epitope
Internal Region
(11), (10), (7), (6), (5), (5), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(107), (43), (42), (24), (23), (22), (12), (12), (9), (6), (3), (1)
Host
Goat
(95), (31), (31)
Clonality
Polyclonal
Conjugate
Un-conjugated
(19), (7), (5), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application
Western Blotting (WB)
(126), (77), (36), (36), (23), (21), (14), (13), (12), (11), (7), (7), (7), (5), (5), (5), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN374802
357.50 $
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Immunogen Peptide from the internal region of the protein sequence according to NP_000393.4 , NP_001035810.1 Genename: G6PD
Sequence C-KPASTNSDDV RDEK
Specificity This antibody detetcs G6PD. It is expected to recognise both reported isoforms (NP_000393.4 and NP_001035810.1).
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, DogSpecies reactivity (tested):Human
Purification Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
Alternative Name G6PD
Background Glucose 6 Phosphate Dehydrogenase (G6PD) produces pentose sugars for nucleic acid synthesis and is the main producer of NADPH reducing power. Catalytic activity: D glucose 6 phosphate + NADP(+) = D glucono 1,5 lactone 6 phosphate + NADPH. Defects in G6PD are the cause of chronic non spherocytic haemolytic anemia (CNSHA). G6PD deficiency is the most common human enzyme deficiency, one benefit of having G6PD deficiency is that it confers a resistance to malaria.Synonyms: Glucose-6-P-Dehydrogenase, Glucose-6-phosphate 1-dehydrogenase
Gene ID 2539, 9606
UniProt P11413
Application Notes Peptide ELISA: antibody detection limit dilution 1: 8000. Western blot: 0.1-0.3 μg/mL. Approx 60 kDa band observed in Human Placenta lysates(calculated MW of 62.0 kDa according to NP_000393.4 and 59.0 kDa according toNP_001035810.1).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.
Supplier Images
anti-Glucose-6-Phosphate Dehydrogenase (G6PD) (Internal Region) antibody anti-Glucose-6-Phosphate Dehydrogenase (G6PD) (Internal Region) antibody
Background publications Guindo, Fairhurst, Doumbo et al.: "X-linked G6PD deficiency protects hemizygous males but not heterozygous females against severe malaria." in: PLoS medicine, Vol. 4, Issue 3, pp. e66, 2007 (PubMed).

Validation Images
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