Acox2 antibody (C-Term, Internal Region)

Catalog No. ABIN374845

This Goat Polyclonal antibody specifically detects Acox2 in WB. It exhibits reactivity toward Human.

Quick Overview for Acox2 antibody (C-Term, Internal Region) (ABIN374845)

Target: Acox2 (Acyl-CoA Oxidase 2, Branched Chain (Acox2))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Acox2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Acox2 Antibody

Binding Specificity: C-Term, Internal Region

Specificity: This antibody reacts to ACOX2.

Cross-Reactivity (Details): Species reactivity (expected):Rabbit.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-QWAQKSPTNTQENP, from the internal region (near the C Terminus) of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/4000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Acox2

Target: Acox2 (Acyl-CoA Oxidase 2, Branched Chain (Acox2))

Alternative Name: ACOX2

Background: ACOX2 belongs to the acyl-CoA oxidases family. It is a branched-chain acyl-CoA oxidase, and is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. It oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids. Mutations resulting in the deficiency of ACOX2 lead to the accumulation of branched fatty acids and bile acid intermediates.Synonyms: 12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase, 12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase, 3-alpha, 7-alpha, ACOX-2, EC=1.17.99.3, Peroxisomal acyl-coenzyme A oxidase 2, THCA-CoA oxidase, THCCox, Trihydroxycoprostanoyl-CoA oxidase

Gene ID: 8309

NCBI Accession: NP_003491

UniProt: Q99424

Pathways: Monocarboxylic Acid Catabolic Process