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DGAT1 antibody (Internal Region)

DGAT1 Reactivity: Human, Mouse, Rat, Dog WB, IHC (p), EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN374862
  • Target See all DGAT1 Antibodies
    DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))
    Binding Specificity
    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 31
    • 21
    • 20
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog
    Host
    • 29
    • 2
    • 1
    Goat
    Clonality
    • 30
    • 2
    Polyclonal
    Conjugate
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DGAT1 antibody is un-conjugated
    Application
    • 27
    • 13
    • 13
    • 11
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Sequence
    C-QNSMKPFKDM DYS
    Specificity
    This antibody recognizes DGAT1.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Canine (Dog).
    Species reactivity (tested):Human, Rat.
    Purification
    Immunoaffinity Chromatography
    Immunogen
    Peptide with sequence from the internal region of the protein sequence according to NP_036211.1.
    Top Product
    Discover our top product DGAT1 Primary Antibody
  • Application Notes
    Peptide ELISA: 1/16000. Western Blot: 0.5 - 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))
    Alternative Name
    DGAT1 (DGAT1 Products)
    Synonyms
    ARAT antibody, ARGP1 antibody, DGAT antibody, C75990 antibody, D15Ertd23e antibody, Dgat antibody, dgat1 antibody, wu:fd36g11 antibody, zgc:77691 antibody, DGAT1 antibody, ABX45 antibody, AS11 antibody, ATDGAT antibody, DIACYLGLYCEROL ACYLTRANSFERASE antibody, F27F23.24 antibody, RDS1 antibody, TRIACYLGLYCEROL BIOSYNTHESIS DEFECT 1 antibody, DDBDRAFT_0202877 antibody, DDBDRAFT_0304727 antibody, DDB_0202877 antibody, DDB_0304727 antibody, zgc:92327 antibody, diacylglycerol O-acyltransferase 1 antibody, diacylglycerol O-acyltransferase 1a antibody, diacylglycerol O-acyltransferase 1 L homeolog antibody, membrane bound O-acyl transferase (MBOAT) family protein antibody, diacylglycerol O-acyltransferase Dga1 antibody, diacylglycerol O-acyltransferase 1b antibody, DGAT1 antibody, Dgat1 antibody, dgat1a antibody, dgat1.L antibody, TAG1 antibody, dgat1 antibody, MGYG_02131 antibody, Tsp_02502 antibody, LOC100283803 antibody, dga1 antibody, dgat1b antibody
    Background
    Glucose and insulin are anabolic signals which upregulate the transcriptions of a series of lipogenic enzymes to convert excess carbohydrate into triglycerides for efficient energy storage. DGAT1 is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. DGAT catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, and lactation. DGAT1 is involved in fat absorption in the intestine and in basal level triglyceride synthesis in adipose tissue, where it is more highly expressed.Synonyms: AGRP1, CAT-related gene product 1, DGAT, DGAT-1, Diacylglycerol O-acyltransferase 1, Diglyceride acyltransferase
    Gene ID
    8694
    NCBI Accession
    NP_036211
    UniProt
    O75907
    Pathways
    Hormone Transport
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