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Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) (C-Term) antibody

Details for Product No. ABIN374940, Supplier: Login to see
Antigen
  • IMP-2
  • IMP2
  • VICKZ2
  • p62
  • C330012H03Rik
  • Imp2
  • Neilsen
  • RGD1305614
Epitope
C-Term
30
16
7
7
5
5
4
2
2
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine)
121
31
24
3
2
1
1
1
1
1
Host
Goat
80
31
15
Clonality
Polyclonal
Conjugate
Un-conjugated
7
6
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
103
55
34
33
27
18
13
11
7
2
1
Supplier
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Immunogen Peptide with sequence C-KQQEQKYPQGVASQR, from the C Terminus of the protein sequence
Specificity This antibody is expected to recognise both reported isoforms of IGF2BP2 (NP_006539.3 and NP_001007226.1).
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Canine.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name IGF2BP2 (IGF2BP2 Antibody Abstract)
Background IGF2BP2 is a member of the IGF-II mRNA binding protein (IMP) family. It contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: Hepatocellular carcinoma autoantigen p62, IGF-II mRNA-binding protein 2, IGF2 mRNA-binding protein 2, IMP-2, IMP2, Insulin-like growth factor 2 mRNA-binding protein 2, VICKZ family member 2, VICKZ2
Gene ID 10644, 9606
UniProt Q9Y6M1
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA
Pathways
Application Notes Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) (C-Term) antibody (ABIN374940) anti-Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) (C-Term) antibody
 image for anti-Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) (C-Term) antibody (ABIN374940) anti-Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) (C-Term) antibody (Image 2)
Background publications Zeggini, Weedon, Lindgren et al.: "Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes. ..." in: Science (New York, N.Y.), Vol. 316, Issue 5829, pp. 1336-41, 2007 (PubMed).