Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) (C-Term) antibody

Details for Product No. ABIN374940
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Antigen
Synonyms p62, IMP2, IMP-2, VICKZ2, RGD1305614, Imp2, Neilsen, C330012H03Rik
Epitope
C-Term
(9), (9), (7), (4), (2), (2), (1), (1), (1), (1)
Reactivity
Dog (Canine), Human, Mouse (Murine)
(67), (19), (17), (13), (10), (6)
Host
Goat
(45), (19), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(52), (27), (17), (17), (13), (10), (9), (4), (3), (2), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN374940
Quantity 0.1 mg
Price
357.50 $   Plus shipping costs $45.00
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Immunogen Peptide with sequence C-KQQEQKYPQGVASQR, from the C Terminus of the protein sequence
Specificity This antibody reacts to IGF2BP2. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse, Canine.
Purification Affinity chromatography
Alternative Name IGF2BP2
Background IGF2BP2 is a member of the IGF-II mRNA binding protein (IMP) family. It contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alternate names: Hepatocellular carcinoma autoantigen p62, IGF-II mRNA-binding protein 2, IGF2 mRNA- binding protein 2, IMP-2, IMP2, Insulin-like growth factor 2 mRNA-binding protein 2, VICKZ family member 2, VICKZ2
Gene ID 10644
NCBI Accession 9606
UniProt Q9Y6M1
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA
Application Notes Peptide ELISA: 1/16000. Western Blot: 1 - 3 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0,5 mg/mL
Buffer Tris buffered saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) (C-Term) antibody anti-Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) (C-Term) antibody
anti-Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) (C-Term) antibody (2) anti-Insulin-Like Growth Factor 2 MRNA Binding Protein 2 (IGF2BP2) (C-Term) antibody (Image 2)
Background publications Zeggini, Weedon, Lindgren et al.: "Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes." in: Science (New York, N.Y.), Vol. 316, Issue 5829, pp. 1336-41, 2007 (PubMed).

Hosts (45), (19), (6)
Reactivities (67), (19), (17), (13), (10), (6)
Applications (52), (27), (17), (17), (13), (10), (9), (4), (3), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (9), (7), (4), (2), (2), (1), (1), (1), (1)
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