IGF2BP2 antibody (C-Term)

Catalog No. ABIN374940

The Goat Polyclonal anti-IGF2BP2 antibody (ABIN374940) specifically detects IGF2BP2 in WB. The antibody is reactive with Human, Mouse and Dog samples.

Quick Overview for IGF2BP2 antibody (C-Term) (ABIN374940)

Target: IGF2BP2 (Insulin-Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2))

Reactivity: Human, Mouse, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This IGF2BP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IGF2BP2 Antibody

Binding Specificity: C-Term

Specificity: This antibody is expected to recognise both reported isoforms of IGF2BP2 (NP_006539.3 and NP_001007226.1).

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Canine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-KQQEQKYPQGVASQR, from the C Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IGF2BP2

Target: IGF2BP2 (Insulin-Like Growth Factor 2 mRNA Binding Protein 2 (IGF2BP2))

Alternative Name: IGF2BP2

Background: IGF2BP2 is a member of the IGF-II mRNA binding protein (IMP) family. It contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.Synonyms: Hepatocellular carcinoma autoantigen p62, IGF-II mRNA-binding protein 2, IGF2 mRNA-binding protein 2, IMP-2, IMP2, Insulin-like growth factor 2 mRNA-binding protein 2, VICKZ family member 2, VICKZ2

Gene ID: 10644, 9606

UniProt: Q9Y6M1