Membrane-Associated Ring Finger (C3HC4) 6, E3 Ubiquitin Protein Ligase (MARCH6) (Internal Region), (AA 701-712) antibody

Details for Product No. ABIN374941
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Antigen
Synonyms RGD1310927, RGD1565757, im:7161807, wu:fa98a02, si:dkey-40c17.2, Mar-06, 3830408G03, F830029L24Rik, mKIAA0597, DOA10, MARCH-VI, RNF176, TEB4
Epitope
Internal Region, AA 701-712
(5), (4), (3), (3), (1), (1)
Reactivity
Human, Mouse (Murine)
(33), (19), (17), (17), (17), (17), (17)
Host
Goat
(18), (11), (5)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(15), (14), (14), (10), (5), (1)
Pubmed 2 references available
Quantity 0.1 mg
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Catalog No. ABIN374941
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Immunogen Peptide with sequence from the internal region of the protein sequence according to NP_005876.2 Genename: MARCH6
Sequence C-QGRRVIFQKV KE
Specificity This antibody recognizes TEB4 / MARCH-VI (701-712). Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse.
Purification Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Alternative Name MARCH6 / RNF176
Background MARCH6 (Membrane associated RING finger protein 6) belongs to the MARCH family, which contains at least seven membrane associated RING-CH (MARCH)proteins. MARCH proteins are E3 ubiquitin ligases and are located to subcellular membranes.
Alternate names: Doa10 homolog, E3 ubiquitin-protein ligase MARCH6, KIAA0597, MARCH-VI, Membrane- associated RING finger protein 6, Membrane-associated RING-CH protein VI, Protein TEB-4, RING finger protein 176, TEB-4, TEB4
Gene ID 10299, 9606
UniProt O60337
Application Notes Peptide ELISA: 1/16000. Western Blot: 0.2 - 0.5 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0,5 mg/mL
Buffer Tris buffered saline, pH~7.3 0.02% Sodium Azide 0.5% BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Supplier Images
anti-Membrane-Associated Ring Finger (C3HC4) 6, E3 Ubiquitin Protein Ligase (MARCH6) (Internal Region), (AA 701-712) antibody anti-Membrane-Associated Ring Finger (C3HC4) 6, E3 Ubiquitin Protein Ligase (MARCH6) (Internal Region), (AA 701-712) antibody
Background publications Buckley, Bonner, Brann: "Localization of a family of muscarinic receptor mRNAs in rat brain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 8, Issue 12, pp. 4646-52, 1989 (PubMed).

Kreft, Wang, Hochstrasser: "Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI)." in: The Journal of biological chemistry, Vol. 281, Issue 8, pp. 4646-53, 2006 (PubMed).

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