DYX1C1 antibody (N-Term)

Catalog No. ABIN374955

Product Details anti-DYX1C1 Antibody

Target: DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))

Binding Specificity: N-Term

Reactivity: Human, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This DYX1C1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: PLQVSDYSWQ QTKT-C

Specificity: This antibody is expected to recognizes three reported isomers of Human DYX1C1 / EKN1.

Cross-Reactivity (Details): Species reactivity (expected):Canine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the N Terminus of Human DYX1C1

Application Details

Application Notes: Peptide ELISA: 1/32000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DYX1C1

Target: DYX1C1 (Dyslexia Susceptibility 1 Candidate 1 (DYX1C1))

Alternative Name: DYX1C1 (DYX1C1 Products)

Synonyms: DYX1 antibody, DYXC1 antibody, EKN1 antibody, RD antibody, 1700010I24Rik antibody, Edem2 antibody, Ekn1 antibody, zgc:77853 antibody, LOC100220614 antibody, dynein axonemal assembly factor 4 antibody, dyslexia susceptibility 1 candidate 1 antibody, dynein axonemal assembly factor 4 L homeolog antibody, DNAAF4 antibody, Dyx1c1 antibody, Dnaaf4 antibody, dnaaf4 antibody, DYX1C1 antibody, dnaaf4.L antibody

Background: DYX1C1 is expressed in several tissues, including brain, lung, kidney and testis. In brain, it localizes to a fraction of cortical neurons and white matter glial cells. An aberration involving DYX1C1 may be a cause of dyslexia.Synonyms: Dyslexia susceptibility 1 candidate gene 1 protein, EKN1

Molecular Weight: 48.5 kDa (NP_570722.2) and 44.0 kDa (NP_001028731.1)

Gene ID: 161582

NCBI Accession: NP_001028731

UniProt: Q8WXU2

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling