CHRNB1 antibody (Internal Region, Subunit beta)

Catalog No. ABIN374964

Product Details anti-CHRNB1 Antibody

Target: CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

Binding Specificity: Internal Region, Subunit beta

Reactivity: Human, Mouse, Rat, Cow

Host: Goat

Clonality: Polyclonal

Conjugate: This CHRNB1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: C-QEQEDHDALK ED

Specificity: This antibody recognizes CHRNB1 / ACHRB.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_000738.2 Genename: CHRNB1

Application Details

Application Notes: Peptide ELISA: 1/1000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CHRNB1

Target: CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

Alternative Name: Acetylcholine Receptor beta Subunit (CHRNB1 Products)

Synonyms: CHRNB1 antibody, ACHRB antibody, CHRNB antibody, CMS1D antibody, CMS2A antibody, SCCMS antibody, Acrb antibody, RNACRB1 antibody, Achr-2 antibody, cholinergic receptor nicotinic beta 1 subunit antibody, cholinergic receptor, nicotinic, beta 1 (muscle) antibody, acetylcholine receptor beta subunit antibody, cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) antibody, CHRNB1 antibody, chrnb1 antibody, ACHRB antibody, Chrnb1 antibody

Background: After binding acetylcholine, the acetylcholine receptor responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.Synonyms: ACHRB, CHRNB, CHRNB1

Gene ID: 1140, 9606

UniProt: P11230

Pathways: Synaptic Membrane