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Meis Homeobox 1 (MEIS1) (Internal Region) antibody

Details for Product No. ABIN375073, Supplier: Login to see
Antigen
  • meis
  • 1323/07
  • 1422/04
  • CG17117
  • Dm-HTH
  • Dmel\\CG17117
  • HTH
  • Hth
  • Meis1
  • P53
  • anon-EST:Liang-2.13
  • clone 2.13
  • dtl
  • hth1
  • hth2
  • l(3)05745
  • l(3)86Ca
  • C530044H18Rik
  • Evi8
  • cb224
  • id:ibd5078
  • meis1.1
  • wu:fb38b03
  • wu:fc02e11
  • wu:fd12a02
Epitope
Internal Region
9
8
5
4
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
47
17
10
4
3
3
2
2
1
1
1
1
1
Host
Goat
34
14
2
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
Application
Western Blotting (WB)
39
21
6
4
1
1
1
1
Supplier
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Immunogen Peptide with sequence C-SEDITRSANLTDQ, from the internal region of the protein sequence
Specificity This antibody reacts to MEIS1.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, Bovine.
Species reactivity (tested):Human.
Purification Affinity chromatography
Alternative Name MEIS1 (MEIS1 Antibody Abstract)
Background MEIS1 is a member of the TALE (three amino acid loop extension) family of homeodomain containing proteins. In addition to binding with other Hox proteins, MEIS1 also forms heterodimers with the ubiquitously expressed Pbx proteins, including Pbx1, Pbx2 and Pbx3, and these complexes contain distinct DNA binding specificities. MEIS1 is implicated in oncogenesis as it is overexpressed as a result of adjacent retroviral insertion in BHX2 myeloid leukemias. It plays an important role in megakaryocytic gene expression.Synonyms: Homeobox protein Meis1
Gene ID 4211, 9606
UniProt O00470
Research Area Stem Cells, Hematopoietic Progenitors, Transcription Factors
Pathways
Application Notes Peptide ELISA: 1/32000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0,5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
 image for anti-Meis Homeobox 1 (MEIS1) (Internal Region) antibody (ABIN375073) anti-Meis Homeobox 1 (MEIS1) (Internal Region) antibody
Background publications Wong, Iwasaki, Somervaille et al.: "Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential." in: Genes & development, Vol. 21, Issue 21, pp. 2762-74, 2007 (PubMed).