Fibroblast Growth Factor Receptor 2 (FGFR2) (Internal Region) antibody

Details for Product No. ABIN375199
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Antigen
Synonyms
FGFR2, FGFR2IIIb, bek, bfr-1, cd332, cek3, cfd1, ect1, fgfr-2, jws, k-sam, kgfr, tk14, tk25, xfgfr2, DKFZp469H1521, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, AU043015, A ... show more
FGFR2, FGFR2IIIb, bek, bfr-1, cd332, cek3, cfd1, ect1, fgfr-2, jws, k-sam, kgfr, tk14, tk25, xfgfr2, DKFZp469H1521, BBDS, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, AU043015, AW556123, Bek, Fgfr-2, Fgfr-7, Fgfr7, KGFRTr, svs, FGF-R, fgfr72IIIb, FGFR, fc56c05, wu:fc56c05 show less
Epitope
Internal Region
(24), (20), (13), (12), (6), (6), (6), (5), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(161), (44), (37), (3), (2)
Host
Goat
(133), (31), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(130), (67), (50), (47), (42), (33), (17), (10), (9), (7), (6), (2)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN375199
357.50 $
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Immunogen Peptide with sequence C-GREKEITASPDY, from the internal region of the protein sequence
Specificity This antibody reacts to FGFR2.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.
Purification Ammonium sulphate precipitation followed by antigen affinity chromatography
Alternative Name CD332 / FGFR-2
Background Fibroblast growth factors (FGFs) are members of a large family of structurally related polypeptides that are potent physiological regulators of growth and differentiation for a wide variety of cells of mesodermal, ectodermal and endodermal origin. Four genes encoding for high affinity cell surface FGF receptors (FGFRs) have been identified: FGFR1, FGFR2, FGFR3 and FGFR4. FGFRs are members of the tyrosine kinase family of growth factor receptors. FGFR2 is highly expressed in developing human tissues including the brain, choroids plexus, lung etc.Synonyms: BEK, FGFR2, Fibroblast growth factor receptor 2, KGFR, KSAM, Keratinocyte growth factor receptor 2
Gene ID 2263
NCBI Accession NP_000132
UniProt P21802
Research Area Growth Factors, Receptors
Application Notes ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (Internal Region) antibody anti-Fibroblast Growth Factor Receptor 2 (FGFR2) (Internal Region) antibody
Background publications McGrath, Lee, Buring et al.: "Novel breast cancer risk alleles and endometrial cancer risk." in: International journal of cancer. Journal international du cancer, Vol. 123, Issue 12, pp. 2961-4, 2008 (PubMed).

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