GATA5
Reactivity: Rat, Mouse
WB
Host: Rabbit
Polyclonal
unconjugated
Application Notes
ELISA: 1/32000. Western Blot: 0.3 - 1 μg/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
0,5 mg/mL
Buffer
Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
The protein encoded by this gene is a transcription factor that contains two GATA type zinc fingers. The encoded protein is known to bind to hepatocyte nuclear factor-1alpha (HNF 1 alpha), and this interaction is essential for cooperative activation of the intestinal lactase phlorizin hydrolase promoter. In other organisms, similar proteins may be involved in the establishment of cardiac smooth muscle cell diversity. GATA5 is induced at an early stage of endothelial-endocardial differentiation prior to expression of such early endocardial markers as Tie2 and ErbB3. It is required for differentiation of cardiogenic precursors into endothelial endocardial cells.Synonyms: GATA-5, GATA-binding factor 5, Transcription factor GATA-5