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Details for Product No. ABIN388085

SMT3 Suppressor of Mif Two 3 Homolog 2 (S. Cerevisiae) (SUMO2) (C-Term), (AA 63-93) antibody

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Antigen
Synonyms
HSMT3, SMT3B, SMT3H2, SUMO3, Smt3A, sumo2, zgc:92241, Smt3h2, SUMO-2, Smt3b, hsmt3, smt3b, smt3h2, sumo-2, PSMT3, ATSUMO2, MCO15.11, MCO15_11, SMALL UBIQUITIN-LIKE MODIFIER 2, SUM2, SUMO 2, small ubiq ... show more
Epitope
»Alternatives C-Term, AA 63-93
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (IHC), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN388085
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This SUMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 AA from the C-terminal region of human SUMO2.
Clone RB2761
Isotype Ig
Specificity This SUMO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SUMO2.
Predicted Reactivity Cow (Bovine),Chicken,Hamster,Mouse (Murine),Pig (Porcine),Monkey,Rat (Rattus),Xenopus laevis,Zebrafish
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name SUMO2
Background SUMO2 is a member of the SUMO (small ubiquitin-like modifier) protein family. This protein family functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. In vertebrates, three members of the SUMO family have been described, SUMO 1 and the functionally distinct homologues SUMO 2 and SUMO 3. SUMO modification sites present in the N terminal regions of SUMO 2 and SUMO 3 are utilized by SAE1/SAE2 (SUMO E1) and Ubc9 (SUMO E2) to form polymeric chains of SUMO 2 and SUMO 3 on protein substrates, a property not shared by SUMO 1.
Synonyms: Small ubiquitin-related modifier 2, SUMO-2, Ubiquitin-like protein SMT3B, SMT3 homolog 2, Sentrin-2, HSMT3, SUMO-3, SMT3B, SMT3H2
Molecular Weight 11637 DA
Gene ID 6613
UniProt P61956
Research Area Apoptosis/Necrosis, Translation Factors, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes Recommend dilutions: IHC : 1:50-100,WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Lapenta, Chiurazzi, van der Spek et al.: "SMT3A, a human homologue of the S. cerevisiae SMT3 gene, maps to chromosome 21qter and defines a novel gene family." in: Genomics, Vol. 40, Issue 2, pp. 362-6, 1997 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Mori, Miki, Tanji et al.: "Incipient intranuclear inclusion body disease in a 78-year-old woman." in: Neuropathology : official journal of the Japanese Society of Neuropathology, 2010 (PubMed).

Alternatives for antigen "SMT3 Suppressor of Mif Two 3 Homolog 2 (S. Cerevisiae) (SUMO2)", type "Antibodies"
Hosts (45), (10)
Reactivities (55), (22), (22), (13), (12), (3), (2), (1), (1)
Applications (45), (27), (17), (10), (7), (4), (1), (1), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (5), (4), (2), (2), (1)
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