|+1 404 474 4654|
|+1 888 205 9894 (TF)|
MAP-2 (C-Term) antibody
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), ELISA
|3 references available|
|Quantity||400 µL (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This MAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418~447 amino acids from the C-terminal region of human MAP2.|
|Description||Other names: Microtubule-associated protein 2, MAP-2, MAP2|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This MAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 418~447 amino acids from the C-terminal region of human MAP2.|
|Molecular Weight||199610 DA|
Background: This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The exact function of this gene is still unknown. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development.
|Application Notes||The suggested dilution will be: ELISA~~1:1,000 Immunohistochemistry~~1:50~100 Western Blot ~~ 1:100~500|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Stem Cells, Signaling, Neurology, Cell Structure|
|Restrictions||For Research Use only|
DeTure, Di Noto, Purich: "In vitro assembly of Alzheimer-like filaments. How a small cluster of charged residues in Tau and MAP2 controls filament morphology." in: The Journal of biological chemistry, Vol. 277, Issue 38, pp. 34755-9, 2002 (PubMed).
Al-Bassam, Ozer, Safer et al.: "MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments." in: The Journal of cell biology, Vol. 157, Issue 7, pp. 1187-96, 2002 (PubMed).
Liu, Saad, Shen et al.: "Diagnostic value of microtubule-associated protein-2 (MAP-2) for neuroendocrine neoplasms." in: Advances in anatomic pathology, Vol. 10, Issue 2, pp. 101-6, 2003 (PubMed).