Neurogenin 1 antibody (N-Term)

Catalog No. ABIN388767

Product Details anti-Neurogenin 1 Antibody

Target: Neurogenin 1 (NEUROG1)

Binding Specificity: AA 31-60, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurogenin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Neurogenin1 (NeuroG1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human Neurogenin1 (NeuroG1).

Clone: RB02905

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Neurogenin 1

Target: Neurogenin 1 (NEUROG1)

Alternative Name: Neurogenin1 (NeuroG1) (NEUROG1 Products)

Synonyms: ath4c antibody, neurogenin-1 antibody, ngn1 antibody, NEUROG1 antibody, aka antibody, ngn antibody, math4c antibody, neurod3 antibody, neurogenin antibody, neurogenin1 antibody, AKA antibody, Math4C antibody, Neurod3 antibody, bHLHa6 antibody, NEUROD3 antibody, Ngn1 antibody, cb260 antibody, chunp6899 antibody, ngr1 antibody, zNgn1 antibody, neurogenin 1 antibody, NEUROG1 antibody, neurog1 antibody, Neurog1 antibody

Background: Basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.

Gene ID: 4762

NCBI Accession: NP_006152

UniProt: Q92886