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Dystrobrevin Binding Protein 1 (DTNBP1) (AA 296-325), (C-Term) antibody

Details for Product No. ABIN389170, Supplier: Log in to see
Antigen
  • SDY
  • CG6856
  • Ddysb
  • Dmel\\CG6856
  • dtnbp1
  • zgc:56462
  • MGC83903
  • sdy
  • dbnd
  • hps7
  • my031
  • MGC85477
  • DTNBP1
  • BLOC1S8
  • DBND
  • HPS7
  • My031
  • 5430437B18Rik
  • AW048963
  • Bloc1s8
  • dysbindin
Epitope
AA 296-325, C-Term
37
19
16
3
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
95
31
22
13
1
Host
Rabbit
105
5
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
8
8
8
6
6
6
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
79
51
40
22
12
6
3
2
1
1
1
Supplier
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Immunogen This Dtnbp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-325 AA from the C-terminal region of human Dtnbp1.
Clone RB9241
Isotype Ig
Specificity This Dtnbp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303~333 amino acids from the C-terminal region of mouse Dtnbp1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Dtnbp1 (DTNBP1 Antibody Abstract)
Background Dtnp1 may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and binds to alpha- and beta-dystrobrevins, which are components of the dystrophin-associated protein complex (DPC). Mutations in this protein are associated with Hermansky-Pudlak syndrome type 7. This protein may also be associated with schizophrenia.
Synonyms: Dysbindin, Dystrobrevin-binding protein 1, Hermansky-Pudlak syndrome 7 protein homolog, Hps7-like protein, Dtnbp1, Sdy
Molecular Weight 39651 DA
Gene ID 94245
UniProt Q91WZ8
Research Area Stem Cells
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 296-325), (C-Term) antibody (ABIN389170) Western blot analysis of Dtnbp1(arrow) using rabbit polyclonal Dysbindin(Dtnbp1) Anti...
Immunohistochemistry (IHC) image for anti-Dystrobrevin Binding Protein 1 (DTNBP1) (AA 296-325), (C-Term) antibody (ABIN389170) Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with Dtnbp1...
Background publications Benson, Newey, Martin-Rendon et al.: "Dysbindin, a novel coiled-coil-containing protein that interacts with the dystrobrevins in muscle and brain." in: The Journal of biological chemistry, Vol. 276, Issue 26, pp. 24232-41, 2001 (PubMed).