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MMP11 antibody (Matrix Metallopeptidase 11 (Stromelysin 3)) (AA 398-426)

Details for Product anti-MMP11 Antibody No. ABIN390135, Supplier: Log in to see
Antigen
  • SL-3
  • ST3
  • STMY3
  • Stmy3
Epitope
AA 398-426, C-Term
32
15
7
7
5
5
5
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
106
36
29
2
1
Host
Rabbit
96
27
1
Clonality (Clone)
Polyclonal ()
Conjugate
This MMP11 antibody is un-conjugated
12
7
4
4
4
4
1
1
1
1
1
1
1
Application
Western Blotting (WB)
93
61
47
25
15
14
8
7
5
3
3
1
Supplier
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Immunogen This MMP11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 398-426 AA from the C-terminal region of human MMP11.
Clone RB2023
Isotype Ig
Specificity This MMP11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MMP11.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name MMP11 (MMP11 Antibody Abstract)
Background Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP11 may play an important role in the progression of epithelial malignancies. It is specifically expressed in stromal cells of breast carcinomas.
Molecular Weight 54595 DA
Gene ID 4320
NCBI Accession NP_005931
Research Area Stem Cells, Protein Modifications, Cancer, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-MMP11 antibody (Matrix Metallopeptidase 11 (Stromelysin 3)) (AA 398-426) (ABIN390135) Western blot analysis of anti-MMP11 Antibody (C-term)(ABIN390135) in 293 cell line ly...
Background publications Anglard, Melot, Guérin, Thomas, Basset: "Structure and promoter characterization of the human stromelysin-3 gene." in: The Journal of biological chemistry, Vol. 270, Issue 35, pp. 20337-44, 1995

Basset, Bellocq, Wolf, Stoll, Hutin, Limacher, Podhajcer, Chenard, Rio, Chambon: "A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas." in: Nature, Vol. 348, Issue 6303, pp. 699-704, 1991