2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) antibody

Antigen: 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1)

Synonyms: OIAS, IFI-4, OIASI, OAS1, OAS1Z, DKFZp459F079

Epitope: C-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN390164

Additional Information

Characteristics: Purified Rabbit Polyclonal Antibody (Pab)

Alternative name: OAS1 (C-term)

Gene ID: 4938

Swiss-Prot: P00973

Immunogen: This OAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 309~339 amino acids selected from the C-terminal region of human OAS1.

Isotype: Ig  (Matching secondary antibodies)

Description: Other names: 2-5-oligoadenylate synthetase 1, (2-5)oligo(A) synthetase 1, 2-5A synthetase 1, p46/p42 OAS, E18/E16

Specificity: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected selected from the C-terminal region of human OAS1.

Molecular Weight: 46058 DA

Application Details

Application Notes: ELISA~~1:1,000 Western blotting~~1:100~500 Immunohistochemistry ~~ 1:10~50

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Structure

Restrictions: For Research Use only

Images

The anti-OAS1 Pab (ABIN390164) is used in Western blot to detect OAS1 in mouse liver lysate.

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with OAS1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. clinical relevance has not been evaluated.

Publications

Publications: Gielen, Johnston, Edwards: "Azithromycin induces anti-viral responses in bronchial epithelial cells." in: The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology, 2010 (PubMed).