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CAMK2A antibody (Calcium/calmodulin-Dependent Protein Kinase II alpha) (AA 446-478)

Details for Product anti-CAMK2A Antibody No. ABIN391311, Supplier: Login to see
Antigen
  • camk2
  • camk2b
  • zgc:112538
  • zgc:123320
  • CAMKA
  • CaMKII
  • R74975
  • mKIAA0968
  • PK2CDD
  • PKCCD
Alternatives
anti-Human CAMK2A antibody for Western Blotting
Epitope
AA 446-478, C-Term
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2
1
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1
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Reactivity
Human
126
82
66
10
9
8
5
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3
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2
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Host
Rabbit
119
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18
Clonality (Clone)
Polyclonal ()
Conjugate
This CAMK2A antibody is un-conjugated
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1
1
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1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
179
88
56
43
30
26
22
9
7
2
2
2
2
1
Supplier
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Immunogen This CAMK2A (CAMK2 alpha) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 446-478 AA from the C-terminal region of human CAMK2A (CAMK2 alpha).
Clone RB1258
Isotype Ig
Specificity This CAMK2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CAMK2.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name CAMK2A (CAMK2 alpha) (CAMK2A Antibody Abstract)
Background CaM-kinase II (CAMK2) is a prominent Ser/Thr protein kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Likely autophosphorylation of Thr-286 allows the kinase to switch from a calmodulin-dependent to a calmodulin-independent state. CAMK2 is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits.
Synonyms: Calcium/calmodulin-dependent protein kinase type II alpha chain, CaM-kinase II alpha chain, CaM kinase II alpha subunit, CaMK-II alpha subunit
Molecular Weight 54029 DA
Gene ID 815
UniProt Q9UQM7
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Neurology, Cell Structure
Pathways WNT Signaling, Interferon-gamma Pathway
Application Notes WB = 1:1000, IHC (p) = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 1.64 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-CAMK2A antibody (Calcium/calmodulin-Dependent Protein Kinase II alpha) (AA 446-478) (ABIN391311) Western blot analysis of anti-CAMK2 alpha C-term Pab (ABIN391311) in 293 cell lysate....
Immunohistochemistry (IHC) image for anti-CAMK2A antibody (Calcium/calmodulin-Dependent Protein Kinase II alpha) (AA 446-478) (ABIN391311) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Immunohistochemistry (IHC) image for anti-CAMK2A antibody (Calcium/calmodulin-Dependent Protein Kinase II alpha) (AA 446-478) (ABIN391311) Formalin-fixed and paraffin-embedded human brain tissue reacted with CAMK2 alpha Anti...
Background publications Blume-Jensen, Hunter: "Oncogenic kinase signalling." in: Nature, Vol. 411, Issue 6835, pp. 355-65, 2001 (PubMed).