LKB1 antibody (N-Term)

Catalog No. ABIN391352

The Rabbit Polyclonal anti-LKB1 antibody is suitable to detect LKB1 in samples from Human. It has been validated for WB, IF and FACS.

Quick Overview for LKB1 antibody (N-Term) (ABIN391352)

Target: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LKB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: RB11660

Product Details anti-LKB1 Antibody

Binding Specificity: AA 19-48, N-Term

Predicted Reactivity: C, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This STK11 (LKB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human STK11 (LKB1).

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for LKB1

Target: LKB1 (STK11) (serine/threonine Kinase 11 (STK11))

Alternative Name: STK11 (LKB1)

Background: STK11, is a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms.

Molecular Weight: 48636

Gene ID: 6794

NCBI Accession: NP_000446

UniProt: Q15831

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect