Phosphinothricin N-Acetyltransferase (BAR2) (AA 236-264), (Ser261) antibody

Details for Product No. ABIN391397
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Antigen
Epitope
AA 236-264, Ser261
(2), (1), (1)
Reactivity
Human, Mouse (Murine)
(3)
Host
Rabbit
(3)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(2), (1)
Pubmed 2 references available
Catalog no. ABIN391397
Quantity 400 µL
Price
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Immunogen This BAR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-264 AA from human BAR2.
Clone RB15325
Isotype Ig
Specificity This BAR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243~272 amino acids surrounding S261 of human BAR2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BAR2
Background Beta-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor.
Synonyms: Beta-2 adrenoceptor, Beta-2 adrenoreceptor, ADRB2, ADRB2R, B2AR
Molecular Weight 46426 DA
Gene ID 154
UniProt NP_000015
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Phosphinothricin N-Acetyltransferase (BAR2) (AA 236-264), (Ser261) antibody Western blot analysis of anti-BAR2 Antibody (S261) (ABIN391397) in mouse kidney lysates (35 µg/lane). BAR2 (arrow) was detected using the purified polyclonal antibody (1:60 dilution).
anti-Phosphinothricin N-Acetyltransferase (BAR2) (AA 236-264), (Ser261) antibody (2) Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with BAR2 Antibody (S261) (ABIN391397), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Product cited in: Simkins, Crawford, Goudreau et al.: "Enhanced Humoral Immunity in Mice Lacking CB1 and CB2 Receptors (Cnr1 (-/-) /Cnr2 (-/-) Mice) is not Due to Increased Splenic Noradrenergic Neuronal Activity." in: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2014 (PubMed).

Background publications Cherezov, Rosenbaum, Hanson et al.: "High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor." in: Science (New York, N.Y.), Vol. 318, Issue 5854, pp. 1258-65, 2007 (PubMed).

Hosts (3)
Reactivities (3)
Applications (2), (1)
Epitopes (2), (1), (1)
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