ADAM9 antibody (N-Term)

Catalog No. ABIN391640

There are 2+ publications for this product available. The Rabbit Polyclonal anti-ADAM9 antibody is suitable to detect ADAM9 in samples from Human and Mouse. It has been validated for WB and FACS.

Quick Overview for ADAM9 antibody (N-Term) (ABIN391640)

Target: ADAM9 (ADAM Metallopeptidase Domain 9 (ADAM9))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAM9 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB17776

Product Details anti-ADAM9 Antibody

Binding Specificity: AA 35-64, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ADAM9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-64 amino acids from the N-terminal region of human ADAM9.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-ADAM9 antibody (ABIN391640)

Chen, Chang: "Arecoline-induced death of human leukemia K562 cells is associated with surface up-modulation of TNFR2." in: Journal of cellular physiology, Vol. 227, Issue 5, pp. 2240-51, (2012) (PubMed).

Liu, Chang: "Suppression of ADAM17-mediated Lyn/Akt pathways induces apoptosis of human leukemia U937 cells: Bungarus multicinctus protease inhibitor-like protein-1 uncovers the cytotoxic mechanism." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30506-15, (2010) (PubMed).

Target Details for ADAM9

Target: ADAM9 (ADAM Metallopeptidase Domain 9 (ADAM9))

Alternative Name: ADAM9

Background: ADAM9 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This protein interacts with SH3 domain-containing proteins, binds mitotic arrest deficient 2 beta protein, and is also involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

Molecular Weight: 90556

Gene ID: 8754

NCBI Accession: NP_003807

UniProt: Q13443

Pathways: Cellular Response to Molecule of Bacterial Origin, SARS-CoV-2 Protein Interactome