EPH Receptor A7 (EPHA7) antibody

Details for Product No. ABIN391900
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Antigen
Reactivity
Human
(96), (48), (41), (17), (17), (17)
Host
Rabbit
(87), (13), (2), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(5), (4), (4), (4), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(76), (63), (21), (14), (11), (8), (2), (2), (1)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN391900
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Immunogen This EphA7 antibody is generated from rabbits immunized with recombinant human EphA7 protein.
Clone RB14730
Isotype Ig
Specificity This EphA7 antibody is generated from rabbits immunized with recombinant human EphA7 protein.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name EphA7
Background EphA7 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.[1]
Synonyms: Ephrin type-A receptor 7, Tyrosine-protein kinase receptor EHK-3, Eph-homology kinase-3, Receptor protein-tyrosine kinase HEK11
Molecular Weight 112096 DA
Gene ID 2045
UniProt Q15375
Research Area Phospho-specific antibodies, Protein Modifications, Neurology, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-EPH Receptor A7 (EPHA7) antibody Western blot analysis of EphA7 (arrow) using rabbit polyclonal EphA7 Antibody (ABIN391900).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the EphA7 gene (Lane 2) (Origene Technologies).
anti-EPH Receptor A7 (EPHA7) antibody (2) Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with EphA7 antibody (ABIN391900), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Background publications Fox, Holst, Chute et al.: "cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases." in: Oncogene, Vol. 10, Issue 5, pp. 897-905, 1995 (PubMed).

Holder, Klein: "Eph receptors and ephrins: effectors of morphogenesis." in: Development (Cambridge, England), Vol. 126, Issue 10, pp. 2033-44, 1999 (PubMed).

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