Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (C-Term) antibody
| Antigen | Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) |
| Synonyms | CCK, RICK, RIP2, CARD3, GIG30, CARDIAK, RIPK2 |
| Binding Site |
Alternatives C-Term |
| Clonality | Polyclonal |
| Host |
Alternatives Rabbit |
| Reactivity |
Alternatives Human |
| Application |
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), ELISA |
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3 references available |
| Certificates | ISO 9001:2008 |
| Catalog no. | ABIN392274 |
| Quantity | 0.1 mg (0.25 mg/ml) |
| Price | 280.50 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 2 to 3 Business Days |
Additional Information
| Alternative name | RIPK2 |
| Gene ID | 8767 |
| UniProt | NP_003812 |
| Immunogen | This RIPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467~496 amino acids from the C-terminal region of human RIPK2. |
| Isotype | Ig |
| Description | Other names: Receptor-interacting serine/threonine protein kinase 2, RIP-like interacting CLARP kinase, Receptor-interacting protein 2, RIP-2, CARD-containing interleukin-1 beta converting enzyme associated kinase, CARD-containing IL-1 beta ICE-kinase, RIP2 |
| Characteristics | Purified Rabbit Polyclonal Antibody (Pab) |
| Specificity | This RIPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467~496 amino acids from the C-terminal region of human RIPK2. |
| Molecular Weight | 61194 DA |
| Comments |
Background: RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. |
Application Details
| Application Notes | The suggested dilution is: ELISA~~1:1,000 Western blotting~~1:100~500 Immunohistochemistry~~1:50~100 |
| Concentration | 0.25 mg/ml |
| Purification | Purified |
| Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Preca |
| Research Area | Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure |
| Restrictions | For Research Use only |
Images
Publications
| Product |
Chin, Dempsey, Bruhn et al.: "Involvement of receptor-interacting protein 2 in innate and adaptive immune responses." in: Nature, Vol. 416, Issue 6877, pp. 190-4, 2002 (PubMed).
Munz, Hildt, Springer et al.: "RIP2, a checkpoint in myogenic differentiation." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5879-86, 2002 (PubMed). Chen, Clark: "Equilibrium and kinetic folding of an alpha-helical Greek key protein domain: caspase recruitment domain (CARD) of RICK." in: Biochemistry, Vol. 42, Issue 20, pp. 6310-20, 2003 (PubMed). |
Alternatives
Alternatives for antigen "Receptor-Interacting Serine-threonine Kinase 2 (RIPK2)", type "Antibodies"
| Hosts | Rabbit (42), Mouse (6), Rat (3) |
| Reactivities | Human (50), Mouse (Murine) (15), Rat (Rattus) (12), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1) |
| Applications | Western Blotting (WB) (48), ELISA (27), Immunocytochemistry (ICC) (13), Immunohistochemistry (IHC) (7), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunofluorescence (IF) (4), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunoprecipitation (IP) (1) |
| Epitopes | N-Term (10), C-Term (5), AA 508-522 (2), AA 11-30 (1), Internal Region (1), N-Term,AA 11-30 (1), N-Term,AA 38-68 (1), pSer176 (1) |




Alternatives