|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Receptor-Interacting Serine-threonine Kinase 2 (RIPK2) (C-Term) antibody
|Synonyms||CCK, RICK, RIP2, CARD3, GIG30, CARDIAK, RIPK2|
Alternatives Western Blotting (WB), Immunohistochemistry (IHC), ELISA
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This RIPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467~496 amino acids from the C-terminal region of human RIPK2.|
|Description||Other names: Receptor-interacting serine/threonine protein kinase 2, RIP-like interacting CLARP kinase, Receptor-interacting protein 2, RIP-2, CARD-containing interleukin-1 beta converting enzyme associated kinase, CARD-containing IL-1 beta ICE-kinase, RIP2|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This RIPK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467~496 amino acids from the C-terminal region of human RIPK2.|
|Molecular Weight||61194 DA|
Background: RIPK2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
|Application Notes||The suggested dilution is: ELISA~~1:1,000 Western blotting~~1:100~500 Immunohistochemistry~~1:50~100|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.Preca|
|Research Area||Apoptosis/Necrosis, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure|
|Restrictions||For Research Use only|
Chin, Dempsey, Bruhn et al.: "Involvement of receptor-interacting protein 2 in innate and adaptive immune responses." in: Nature, Vol. 416, Issue 6877, pp. 190-4, 2002 (PubMed).
Munz, Hildt, Springer et al.: "RIP2, a checkpoint in myogenic differentiation." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5879-86, 2002 (PubMed).
Chen, Clark: "Equilibrium and kinetic folding of an alpha-helical Greek key protein domain: caspase recruitment domain (CARD) of RICK." in: Biochemistry, Vol. 42, Issue 20, pp. 6310-20, 2003 (PubMed).
|Hosts||Rabbit (42), Mouse (6), Rat (3)|
|Reactivities||Human (50), Mouse (Murine) (15), Rat (Rattus) (12), Chicken (1), Cow (Bovine) (1), Dog (Canine) (1)|
|Applications||Western Blotting (WB) (48), ELISA (27), Immunocytochemistry (ICC) (13), Immunohistochemistry (IHC) (7), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (6), Immunofluorescence (IF) (4), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1), Immunoprecipitation (IP) (1)|
|Epitopes||N-Term (10), C-Term (5), AA 508-522 (2), AA 11-30 (1), Internal Region (1), N-Term,AA 11-30 (1), N-Term,AA 38-68 (1), pSer176 (1)|