FKBP1B antibody (N-Term)

Catalog No. ABIN392348

The Rabbit Polyclonal anti-FKBP1B antibody is suitable to detect FKBP1B in samples from Human and Mouse. It has been validated for WB, IF and IHC (p).

Quick Overview for FKBP1B antibody (N-Term) (ABIN392348)

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP1B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB19308

Product Details anti-FKBP1B Antibody

Binding Specificity: AA 16-46, N-Term

Predicted Reactivity: B, Rb, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This FKBP1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human FKBP1B.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for FKBP1B

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Alternative Name: FKBP1B

Background: FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. The protein is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle.

Molecular Weight: 11783

Gene ID: 2281

NCBI Accession: NP_004107, NP_473374

UniProt: P68106

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity