FKBP1B antibody (AA 1-80)
Quick Overview for FKBP1B antibody (AA 1-80) (ABIN7267212)
Target
See all FKBP1B AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-80
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Purpose
- FKBP1B Rabbit pAb
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Sequence
- MGVEIETISP GDGRTFPKKG QTCVVHYTGM LQNGKKFDSS RDRNKPFKFR IGKQEVIKGF EEGAAQLGPL SPLPICPHPC
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 1-80 of human FKBP1B (NP_473374.1).
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))
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Alternative Name
- FKBP1B
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Background
- The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.,FKBP1B,FKBP12.6,FKBP1L,OTK4,PKBP1L,PPIase,Immunology & Inflammation,Neuroscience,Calcium Signaling,FKBP1B
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Molecular Weight
- 8kDa/11kDa
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Gene ID
- 2281
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UniProt
- P68106
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Pathways
- Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity
Target
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