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SIK2 antibody

SIK2 Reactivity: Human WB, IP, IF, ICC, IHC (p) Host: Mouse Monoclonal S15G10 unconjugated
Catalog No. ABIN400680
  • Target See all SIK2 Antibodies
    SIK2 (Salt-Inducible Kinase 2 (SIK2))
    Reactivity
    • 42
    • 27
    • 13
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 47
    • 7
    • 2
    Mouse
    Clonality
    • 50
    • 6
    Monoclonal
    Conjugate
    • 29
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIK2 antibody is un-conjugated
    Application
    • 47
    • 30
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Characteristics
    Synonyms: SIK-2, SNF1LK2, QIK, Serine/threonine-protein kinase SIK2, Salt-inducible protein kinase 2,Serine/threonine-protein kinase SNF1-like kinase 2, Qin-induced kinase
    Purification
    Affinity Chromatography.
    Immunogen
    Recombinant Human SIK2.
    Clone
    S15G10
    Isotype
    IgG1
    Top Product
    Discover our top product SIK2 Primary Antibody
  • Application Notes
    Western blot. Immunoprecipitation. Immunofluorescence. Immunohistochemistry on Paraffin Sections: 10 µg/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.2 containing 0.09% Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8°C. DO NOT FREEZE! Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    SIK2 (Salt-Inducible Kinase 2 (SIK2))
    Alternative Name
    SIK2 (SIK2 Products)
    Synonyms
    PIG33 antibody, SC1 antibody, LOH11CR1I antibody, QIK antibody, SNF1LK2 antibody, G630080D20Rik antibody, Snf1lk2 antibody, RGD1559698 antibody, si:dkey-27p23.1 antibody, snf1lk2a antibody, SPARC like 1 antibody, salt inducible kinase 2 antibody, salt-inducible kinase 2 antibody, salt-inducible kinase 2a antibody, SPARCL1 antibody, SIK2 antibody, SLK2 antibody, Sik2 antibody, sik2a antibody
    Background
    Snf1lk2 belongs to the Ser/Thr protein kinase family, AMPK subfamily. It has one proteinkinase domain and one UBA domain. Snf1lk2 requires magnesium as a cofactor andphosphorylates Ser-794 of IRS1 in insulin-stimulated adipocytes. This potentiallymodulates the efficiency of insulin signal transduction. It also inhibits CREB activity byphosphorylating and repressing the CREB-specific coactivators, CRTC1-3. Snf1lk2 isactivated by phosphorylation on Thr-175 by STK11 in complex with STE20-relatedadapter-alpha (STRAD alpha) pseudo kinase and CAB39.
    UniProt
    Q9H0K1
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