S100A7 antibody

Catalog No. ABIN400722

Product Details anti-S100A7 Antibody

Target: S100A7 (S100 Calcium Binding Protein A7 (S100A7))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This S100A7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Recognizes S100 Calcium-binding Protein A7 (S100A7).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: S100-A7, S100A7C, PSOR1, S100 calcium-binding protein A7

Purification: Protein G Chromatography

Immunogen: Recombinant Psoriasin/HID-5 protein.

Clone: 47C1068

Isotype: IgG1

Application Details

Application Notes: Western blot. Immunohistochemistry on Paraffin Sections: 10 μg/mL. This antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by alkalinephosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS, 0.05 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for S100A7

Target: S100A7 (S100 Calcium Binding Protein A7 (S100A7))

Alternative Name: S100A7 / Psoriasin (S100A7 Products)

Synonyms: PSOR1 antibody, S100A7c antibody, S100A7 antibody, S100 calcium binding protein A7 antibody, protein S100-A7 antibody, S100A7 antibody, LOC469501 antibody, LOC713189 antibody, LOC714943 antibody, LOC101104285 antibody, LOC102191570 antibody

Background: Psoriasin/HID-5 was originally identified as an up-regulated protein in psoriatic keratinocytes. Subsequently, this protein was found to have elevated expression in abnormally differentiating primary keratinocytes and in various carcinomas, including ductal carcinoma in situ. Psoriasin/HID-5 may play a role in the establishment or maintenance of these pathologies, and may serve as a diagnostic marker of particular tumor types or abnormally proliferative epithelia.Synonyms: PSOR1, S100 calcium-binding protein A7, S100-A7, S100A7C

Gene ID: 6278

UniProt: P31151

Pathways: S100 Proteins