SLC2A2 antibody

Catalog No. ABIN400751

The Mouse Monoclonal anti-SLC2A2 antibody is suitable to detect SLC2A2 in samples from Human. It has been validated for FACS, IF and IHC (p).

Quick Overview for SLC2A2 antibody (ABIN400751)

Target: SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SLC2A2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 5D1

Product Details anti-SLC2A2 Antibody

Specificity: Recognizes GLUT2 expression on hGlut2-transfected NS0 cells but not on control transfectants. Detects Glut2 on the surface of the human intestinal cell line Caco2 in Flow Cytometry and on fixed cells in Immunocytochemistry tests. Based on Flow Cytometric tests on transfected cells, this antibody has no cross-reactivity with Human Glut1 or Human Glut3.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: GLUT-2, Glucose transporter 2, Glucose transporter type 2 liver, Solute carrier family 2facilitated glucose transporter member 2

Purification: Protein G Chromatography.

Immunogen: Human Glut2-transfected NS0 cells.

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry. Immunocytochemistry: 10 μg/mLImmunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 5 % Trehalose and 40 % Glycerol.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for SLC2A2

Target: SLC2A2 (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 2 (SLC2A2))

Alternative Name: GLUT2 / SLC2A2

Background: Glut2 belongs to the facilitative glucose transporter protein family that comprises 13 members. It is an integral membrane protein with 12 transmembrane domains. Glut2 is expressed predominantly in liver, intestine, kidney, and pancreatic beta-cells. It is a low-affinity glucose transporter that has been suggested to function as a glucose sensor in pancreatic beta-cells and facilitate either glucose uptake or efflux from cells depending on the nutritional state.Synonyms: GLUT-2, Glucose transporter 2, Glucose transporter type 2 liver, Solute carrier family 2 facilitated glucose transporter member 2

Gene ID: 6514

UniProt: P11168

Pathways: Warburg Effect