Mre11 antibody (AA 578-590)

Catalog No. ABIN401304

The Rabbit Polyclonal anti-Mre11 antibody (ABIN401304) specifically detects Mre11 in WB, EIA and ChIP. The antibody is reactive with Saccharomyces cerevisiae samples.

Quick Overview for Mre11 antibody (AA 578-590) (ABIN401304)

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Reactivity: Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Mre11 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Chromatin Immunoprecipitation (ChIP)

Product Details anti-Mre11 Antibody

Binding Specificity: AA 578-590

Specificity: This antibody is directed against Saccharomyces cerevisiae Mre11 protein.

Purification: Affinity Purified

Immunogen: Synthetic peptide corresponding to amino acids 578-590 of Saccharomyces cerevisiae (baker's yeast) Mre11 protein

Isotype: IgG

Application Details

Application Notes: ELISA: 1/10000 - 1/50000. Western Blot: 1/200 - 1/2000. ChIP.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.19 mg/mL (by UV absorbance at 280 nm)

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH containing 0.01 % (w/v) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for Mre11

Target: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Alternative Name: MRE11

Background: Mre11 (also known as double-strand break repair protein MRE11) is a subunit of a complex with Rad50 and Xrs2 (RMX complex) that functions in repair of DNA double-strand breaks and in telomere stability. Mre11 possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity that appears to be required for RMX function. This nuclear protein is widely conserved and is also involved in meiotic double strand break processing.Synonyms: Double-strand break repair protein MRE11A, HNGS1, MRE11 homolog 1, MRE11 meiotic recombination 11 homolog A, MRE11A

Gene ID: 855264

NCBI Accession: NP_013951

UniProt: P32829

Pathways: DNA Damage Repair