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Paxillin (PXN) (pTyr88) antibody

Antigen

Paxillin (PXN)
Synonyms FLJ16691, Pax, AW108311, AW123232, CG18061, CG18576, CT40481, CT42454, DPaxillin, DPxn, DPxn37, Dpax, PDLP, DmelCG31794, CG31794, LOC397826, wu:fw71f12, PXN, DKFZp469J2119, LOC100220858
Epitope
Alternatives

pTyr88
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Application
Alternatives Immunofluorescence (IF), Western Blotting (WB)
Catalog no. ABIN401593
Quantity 50 µg  (1.0 mg/ml)  (Variants)
Price 240.00 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies Variants back to top

Characteristics Synonyms: FLJ16691
Alternative name Paxillin / PXN
Gene ID 5829
Swiss-Prot P49023
Immunogen The antiserum was produced against synthesized phosphopeptide derived from humanPaxillin around the phosphorylation site of Tyrosine 88 (P-V-Yp-G-S).
Cross-Reactivity Human
Description Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function offocal adhesions, which are critical to cell adhesion and migration. This in turn plays a rolein a wide variety of processes including embryogenesis, organogenesis, wound repair,inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 bindingdomains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e. g. , FAK,Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptorproteins (e. g. , Actin, Vinculin, Crk).
Specificity Paxillin Antibody (AP09486PU) detects endogenous levels of Paxillin only whenphosphorylated at Tyrosine 88. Species: Human. Others not tested.

Application Details
Alternatives Secondary Antibodies Variants back to top

Application Notes Immunofluorescence: 1/100~1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Concentration 1.0 mg/ml
Purification Aff - Purified
Buffer PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azideand 50% Glycerol.
Storage Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing. Shelf life: One year from despatch.
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies Variants back to top

Alternatives for antigen "Paxillin (PXN)", type "Antibodies"
Hosts Rabbit (100), Mouse (7)
Reactivities Human (101), Mouse (Murine) (49), Rat (Rattus) (48), Chicken (4), Dog (Canine) (3), Cow (Bovine) (1), Horse (Equine) (1), Monkey (1), Pig (Porcine) (1), Xenopus laevis (1)
Applications Western Blotting (WB) (82), Immunofluorescence (IF) (37), Immunohistochemistry (IHC) (26), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (23), Flow Cytometry (FACS) (18), Enzyme Immunoassay (EIA) (13), ELISA (10), Immunoprecipitation (IP) (6), ELISA (Detection) (3), Immunocytochemistry (ICC) (2), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
Epitopes pTyr118 (11), pTyr31 (10), pTyr88 (6), C-Term (2), Center (2), pSer178 (2), N-Term (1), Y118 (1), pSer83 (1)