HIC2 antibody (Middle Region)

Catalog No. ABIN404842

This Rabbit Polyclonal antibody specifically detects HIC2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig and Rabbitand has been mentioned in 1 publication.

Quick Overview for HIC2 antibody (Middle Region) (ABIN404842)

Target: HIC2 (Hypermethylated in Cancer 2 (HIC2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIC2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HIC2 Antibody

Binding Specificity: Middle Region

Sequence: KSPPLPPATP GPHLTPDDAA QLSDSQHGSP PAASAPPVAN SASYSELGGT

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 85%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against HIC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HIC2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 615 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HIC2 antibody (ABIN404842)

Collins, Wright, Edwards, Davis, Grinham, Cole, Goward, Aguado, Mallya, Mokrab, Huckle, Beare, Dunham: "A genome annotation-driven approach to cloning the human ORFeome." in: Genome biology, Vol. 5, Issue 10, pp. R84, (2004) (PubMed).

Target Details for HIC2

Target: HIC2 (Hypermethylated in Cancer 2 (HIC2))

Alternative Name: HIC2

Background: HIC2 belongs to the krueppel C2H2-type zinc-finger protein family.
Alias Symbols: HRG22, KIAA1020, ZBTB30, ZNF907
Protein Interaction Partner: HIC2, HIC1, BARD1, LIG4, APP, PDK2, CCNT1,
Protein Size: 615

Molecular Weight: 66 kDa

Gene ID: 23119

NCBI Accession: NM_015094, NP_055909

UniProt: Q96JB3