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HIC2 antibody (Middle Region)

HIC2 Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777438
  • Target See all HIC2 Antibodies
    HIC2 (Hypermethylated in Cancer 2 (HIC2))
    Binding Specificity
    • 15
    • 7
    • 7
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 54
    • 26
    • 9
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig
    Host
    • 48
    • 5
    • 1
    Rabbit
    Clonality
    • 52
    • 2
    Polyclonal
    Conjugate
    • 23
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HIC2 antibody is un-conjugated
    Application
    • 45
    • 22
    • 13
    • 13
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequence
    CKEEEENGKD ASEDSAQSGS EGGSGHASAH YMYRQEGYET VSYGDNLYVC
    Predicted Reactivity
    Cow: 85%, Dog: 85%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Rabbit: 77%, Rat: 85%
    Characteristics
    This is a rabbit polyclonal antibody against HIC2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human HIC2
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 615 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Collins, Wright, Edwards, Davis, Grinham, Cole, Goward, Aguado, Mallya, Mokrab, Huckle, Beare, Dunham: "A genome annotation-driven approach to cloning the human ORFeome." in: Genome biology, Vol. 5, Issue 10, pp. R84, (2004) (PubMed).

  • Target
    HIC2 (Hypermethylated in Cancer 2 (HIC2))
    Alternative Name
    HIC2 (HIC2 Products)
    Synonyms
    HIC2 antibody, hic2 antibody, MGC154932 antibody, HRG22 antibody, ZBTB30 antibody, ZNF907 antibody, AA409108 antibody, mKIAA1020 antibody, zgc:109776 antibody, HIC ZBTB transcriptional repressor 2 antibody, hypermethylated in cancer 2 L homeolog antibody, hypermethylated in cancer 2 antibody, HIC2 antibody, hic2.L antibody, Hic2 antibody, hic2 antibody
    Background
    HIC2 contains 5 C2H2-type zinc fingers and 1 BTB (POZ) domain. It belongs to the krueppel C2H2-type zinc-finger protein family, Hic subfamily and is a transcriptional repressor.
    Alias Symbols: HRG22, KIAA1020, ZBTB30, ZNF907
    Protein Interaction Partner: HIC2, HIC1, BARD1, LIG4, APP, PDK2, CCNT1,
    Protein Size: 615
    Molecular Weight
    66 kDa
    Gene ID
    23119
    NCBI Accession
    NM_015094, NP_055909
    UniProt
    Q96JB3
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