Claudin 18 (CLDN18) antibody
| Antigen |
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| Synonyms |
SFTA5, SFTPJ, DKFZp564B2062, MGC68719, claudin-18, CLDN18, MGC140810 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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 Alternatives Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Pig (Porcine), Dog (Canine)
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Application
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| Catalog no. |
ABIN404887 |
| Quantity |
50 µg (Variants) |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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Claudin-18 / CLDN18
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Gene ID
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CLDN18
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UniProt
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P56856
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Immunogen
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The immunogen for anti-CLDN18 antibody: synthetic peptide directed towards the middle region of human CLDN18
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Sequence
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YHASGHSVAYKPGGFKASTGFGSNTKNKKIYDGGARTEDE VQSYPSKHDY
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Cross-Reactivity
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Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-CLDN18 antibody concentration is 1 mg/ml.
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Description
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CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells (Niimi et al., 2001 [PubMed 11585919]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-282 AY358479.1 28-309 283-1864 AK098474.1 274-1855 1865-2307 BM785703.1 143-585 2308-2868 AK098474.1 2297-2857 2869-3359 AY102073.1 394-884
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Characteristics
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Antigen Size: 261 amino acids
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Molecular Weight
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28kDa
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Application Notes
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WB Suggested Anti-CLDN18 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human Thymus.
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Restrictions
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For Research Use only
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Product
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Karanjawala, Illei, Ashfaq et al.: "New markers of pancreatic cancer identified through differential gene expression analyses: claudin 18 and annexin A8." in: The American journal of surgical pathology, Vol. 32, Issue 2, pp. 188-96, 2008 (PubMed).
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Alternatives for antigen "Claudin 18 (CLDN18)", type "Antibodies"
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Hosts
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Rabbit (15)
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Reactivities
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Human (11), Mouse (Murine) (6), Rat (Rattus) (5), Cow (Bovine) (2), Dog (Canine) (2), Cat (Feline) (1), Chicken (1), Pig (Porcine) (1)
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Applications
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Western Blotting (WB) (15), ELISA (8), Immunohistochemistry (IHC) (3), Immunofluorescence (IF) (2), Flow Cytometry (FACS) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1), Immunoprecipitation (IP) (1)
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Epitopes
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C-Term (3), Internal Region (2), Center (1)
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2013 BioMed Central Research Awards
