Claudin 18 antibody (C-Term)

Catalog No. ABIN2776808

The Rabbit Polyclonal anti-Claudin 18 antibody (ABIN2776808) specifically detects Claudin 18 in WB. The antibody is reactive with Human, Rat, Mouse, Cow, Dog, Horse, Rabbit and Guinea Pig samples.

Quick Overview for Claudin 18 antibody (C-Term) (ABIN2776808)

Target: Claudin 18 (CLDN18)

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 18 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Claudin 18 Antibody

Binding Specificity: C-Term

Purpose: CLDN18 Antibody - C-terminal region

Sequence: PEETNYKAVS YHASGHSVAY KPGGFKASTG FGSNTKNKKI YDGGARTEDE

Predicted Reactivity: Cow: 85%, Dog: 79%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CLDN18. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN18

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8097504

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Claudin 18

Target: Claudin 18 (CLDN18)

Alternative Name: CLDN18

Background:

Background Information: CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells.CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells (Niimi et al., 2001).[supplied by OMIM].

Gene Name: Claudin 18

Alternative Symbols: SFTA5, SFTPJ

Protein Name: Claudin-18

Molecular Weight: 28kDa

Gene ID: 51208

NCBI Accession: NP_001002026

UniProt: P56856

Pathways: Cell-Cell Junction Organization, Hepatitis C