ZFAND5 antibody (Middle Region)

Catalog No. ABIN404940

Cited in 1 publication. The Rabbit Polyclonal anti-ZFAND5 antibody (ABIN404940) specifically detects ZFAND5 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow and Sheep samples.

Quick Overview for ZFAND5 antibody (Middle Region) (ABIN404940)

Target: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZFAND5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ZFAND5 Antibody

Binding Specificity: Middle Region

Purpose: ZFAND5 Antibody - middle region

Sequence: REDKITTPKT EVSEPVVTQP SPSVSQPSTS QSEEKAPELP KPKKNRCFMC

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against ZFAND5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ZFAND5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34409-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-ZFAND5 antibody (ABIN404940)

He, Sun, Ou, Ding: "The protein Zfand5 binds and stabilizes mRNAs with AU-rich elements in their 3'-untranslated regions." in: The Journal of biological chemistry, Vol. 287, Issue 30, pp. 24967-77, (2012) (PubMed).

Target Details for ZFAND5

Target: ZFAND5 (Zinc Finger, AN1-Type Domain 5 (ZFAND5))

Alternative Name: ZFAND5

Background:

Background Information: ZNF216 (ZFAND5) is a potent inhibitory factor for osteoclast differentiation and the mechanism is unlikely due to direct attenuation of the NF-kappa B pathway. It also has redundant and distinct roles in regulating apoptosis.

Gene Name: Zinc finger, AN1-type domain 5

Alternative Symbols: ZA20D2, ZNF216, ZFAND5A

Protein Name: AN1-type zinc finger protein 5

Molecular Weight: 20kDa

Gene ID: 7763

NCBI Accession: NP_005998

UniProt: O76080

Pathways: Platelet-derived growth Factor Receptor Signaling