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Details for Product No. ABIN404960

Recombination Signal Binding Protein For Immunoglobulin kappa J Region-Like (RBPJL) (Middle Region) antibody

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Antigen
Synonyms RBPSUHL, SUHL, Rbpsuhl, rbpsuhl, RBP-L, RBPJL
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Fruit Fly (Drosophila melanogaster), Zebrafish (Danio rerio), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN404960
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-RBPJL antibody: synthetic peptide directed towards the middle region of human RBPJL
Sequence TIIGTESVEFSFSTSLACTLEPVTPVPLISTLELSGGGDV ATLELHGENF
Predicted Reactivity Bovine : 100%, Dog : 100%, Guinea pig : 100%, Horse : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Rabbit : 100%, Rat : 100%, Chicken : 84%
Characteristics This is a rabbit polyclonal antibody against RBPJL. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name RBPJL
Background RBPJL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein. In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). RBPJL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). The protein encoded by this gene is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.
Molecular Weight 57kDa
Gene ID 11317
NCBI Accession NP_055091, NM_014276
UniProt Q5QPV0
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-RBPJL antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Beres, Masui, Swift et al.: "PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L." in: Molecular and cellular biology, Vol. 26, Issue 1, pp. 117-30, 2005 (PubMed).

Alternatives for antigen "Recombination Signal Binding Protein For Immunoglobulin kappa J Region-Like (RBPJL)", type "Antibodies"
Hosts (8), (1)
Reactivities (9), (1), (1), (1)
Applications (9), (3), (3), (2), (2), (2)
Epitopes (6), (2), (2), (2), (1)
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