Recombination Signal Binding Protein For Immunoglobulin kappa J Region-Like (RBPJL) (Middle Region) antibody

Details for Product No. ABIN404960
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Antigen
Synonyms RBPSUHL, SUHL, Rbpsuhl, rbpsuhl, RBP-L, RBPJL
Epitope
Middle Region
(5), (2), (2), (2), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Fruit Fly (Drosophila melanogaster), Zebrafish (Danio rerio), Human
(9), (1), (1), (1)
Host
Rabbit
(8), (1)
Clonality
Polyclonal
Application
Western Blotting (WB)
(9), (3), (2), (2), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN404960
Quantity 50 µg
Price
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Immunogen Synthetic peptide directed towards the middle region of human RBPJL
Sequence TIIGTESVEFSFSTSLACTLEPVTPVPLISTLELSGGGDV ATLELHGENF
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Chicken : 80 %
Characteristics This is a rabbit polyclonal antibody against RBPJL. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name RBPJL
Background RBPJL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein. In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). RBPJL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). The protein encoded by this gene is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.
Molecular Weight 57 kDa
Gene ID 11317
NCBI Accession NM_014276, NP_055091
UniProt Q5QPV0
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 517 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Recombination Signal Binding Protein For Immunoglobulin kappa J Region-Like (RBPJL) (Middle Region) antibody WB Suggested Anti-RBPJL Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysate
Background publications Beres, Masui, Swift et al.: "PTF1 is an organ-specific and Notch-independent basic helix-loop-helix complex containing the mammalian Suppressor of Hairless (RBP-J) or its paralogue, RBP-L." in: Molecular and cellular biology, Vol. 26, Issue 1, pp. 117-30, 2005 (PubMed).

Hosts (8), (1)
Reactivities (9), (1), (1), (1)
Applications (9), (3), (2), (2), (2), (1)
Epitopes (5), (2), (2), (2), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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