GJA3 antibody (N-Term)

Catalog No. ABIN405103

Product Details anti-GJA3 Antibody

Target: GJA3 (Gap Junction Protein, alpha 3, 46kDa (GJA3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Horse, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJA3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ISHIRFWALQ IIFVSTPTLI YLGHVLHIVR MEEKKKEREE EEQLKRESPS

Predicted Reactivity: Horse: 91%, Human: 100%, Mouse: 83%, Pig: 91%, Rat: 90%, Yeast: 91%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against GJA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GJA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 435 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GJA3

Target: GJA3 (Gap Junction Protein, alpha 3, 46kDa (GJA3))

Alternative Name: GJA3 (GJA3 Products)

Background: GJA3 belongs to the connexin family. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Defects in GJA3 are the cause of zonular pulverulent cataract type 3 (CZP3).
Alias Symbols: CX46, CZP3
Protein Interaction Partner: UBC, CAV1, TJP1, PRKCG, MIP, GJA1,
Protein Size: 435

Molecular Weight: 47 kDa

Gene ID: 2700

NCBI Accession: NM_021954, NP_068773

UniProt: Q9Y6H8