GJA3 antibody (N-Term)

Catalog No. ABIN5534077

Product Details anti-GJA3 Antibody

Target: GJA3 (Gap Junction Protein, alpha 3, 46kDa (GJA3))

Binding Specificity: AA 108-139, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This GJA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-139 amino acids from the N-terminal region of human GJA3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.79 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GJA3

Target: GJA3 (Gap Junction Protein, alpha 3, 46kDa (GJA3))

Alternative Name: GJA3 (GJA3 Products)

Synonyms: cx46 antibody, MGC53082 antibody, czp3 antibody, Cx44 antibody, cx48.5 antibody, Cnx46 antibody, Cx43 antibody, Cx46 antibody, Gja-3 antibody, CTRCT14 antibody, CX46 antibody, CZP3 antibody, MGC69466 protein L homeolog antibody, gap junction protein alpha 3 antibody, gap junction protein, alpha 3 antibody, MGC69466.L antibody, gja3 antibody, GJA3 antibody, Gja3 antibody

Background: GJA3, an integral membrane protein, belong to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin is a component of lens fiber gap junctions, can form both junctional and nonjunctional ('hemi-') channels. Defects in GJA3 are the cause of zonular pulverulent cataract type 3 (CZP3), a form of autosomal dominant congenital cataract.

Molecular Weight: 47 kDa

Gene ID: 2700

UniProt: Q9Y6H8