CALCRL antibody (N-Term)

Catalog No. ABIN405454

This Rabbit Polyclonal antibody specifically detects CALCRL in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Goat, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for CALCRL antibody (N-Term) (ABIN405454)

Target: CALCRL (Calcitonin Receptor-Like (CALCRL))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Goat, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CALCRL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CALCRL Antibody

Binding Specificity: N-Term

Sequence: DGNWFRHPAS NRTWTNYTQC NVNTHEKVKT ALNLFYLTII GHGLSIASLL

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 90%

Characteristics: This is a rabbit polyclonal antibody against CALCRL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CALCRL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 461 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CALCRL

Target: CALCRL (Calcitonin Receptor-Like (CALCRL))

Alternative Name: CALCRL

Background: CALCRL is the receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Alias Symbols: CGRPR, CRLR
Protein Interaction Partner: CALCA, CRCP, RAMP3, RAMP2, RAMP1, ADM,
Protein Size: 461

Molecular Weight: 53 kDa

Gene ID: 10203

NCBI Accession: NM_005795, NP_005786

UniProt: Q16602

Pathways: cAMP Metabolic Process