SLC39A5 antibody (N-Term)

Catalog No. ABIN405627

Cited in 1 publication. The Rabbit Polyclonal anti-SLC39A5 antibody (ABIN405627) specifically detects SLC39A5 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit and Horse samples.

Quick Overview for SLC39A5 antibody (N-Term) (ABIN405627)

Target: SLC39A5 (Solute Carrier Family 39 (Metal Ion Transporter), Member 5 (SLC39A5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC39A5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SLC39A5 Antibody

Binding Specificity: N-Term

Purpose: SLC39A5 Antibody - N-terminal region

Sequence: HYLAQLFGLY GENGTLTAGG LARLLHSLGL GRVQGLRLGQ HGPLTGRAAS

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SLC39A5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC39A5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44143-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC39A5 antibody (ABIN405627)

Downey, Hales, Robaire: "Zinc Transport Differs in Rat Spermatogenic Cell Types and Is Affected by Treatment with Cyclophosphamide." in: Biology of reproduction, Vol. 95, Issue 1, pp. 22, (2016) (PubMed).

Target Details for SLC39A5

Target: SLC39A5 (Solute Carrier Family 39 (Metal Ion Transporter), Member 5 (SLC39A5))

Alternative Name: SLC39A5

Background:

Background Information: Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A5 belongs to a subfamily of proteins that show structural characteristics of zinc transporters.Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A5 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM].

Gene Name: Solute carrier family 39 (metal ion transporter), member 5

Alternative Symbols: ZIP5, MYP24, LZT-Hs7

Protein Name: Zinc transporter ZIP5

Molecular Weight: 56kDa

Gene ID: 283375

NCBI Accession: NP_775867

UniProt: Q6ZMH5

Pathways: Transition Metal Ion Homeostasis