AP3M2 antibody (Middle Region)

Catalog No. ABIN406204

This Rabbit Polyclonal antibody specifically detects AP3M2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio) and Guinea Pig.It has been mentioned in 1 publication

Quick Overview for AP3M2 antibody (Middle Region) (ABIN406204)

Target: AP3M2 (Adaptor-Related Protein Complex 3, mu 2 Subunit (AP3M2))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3M2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-AP3M2 Antibody

Binding Specificity: Middle Region

Purpose: AP3M2 Antibody - middle region

Sequence: VVNTITGSTN VGDQLPTGQL SVVPWRRTGV KYTNNEAYFD VIEEIDAIID

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against AP3M2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AP3M2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52255-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-AP3M2 antibody (ABIN406204)

Su, Ma, Li, Liu, Huang: "Pedicle screw fixation of the cervical spine: guidance by computed tomography." in: Clinical orthopaedics and related research, Vol. 462, pp. 99-104, (2007) (PubMed).

Target Details for AP3M2

Target: AP3M2 (Adaptor-Related Protein Complex 3, mu 2 Subunit (AP3M2))

Alternative Name: AP3M2

Background:

Targeted Subunit: mu-2

Background Information: AP3M2 is part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes.This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 3 (AP-3), which belongs to the adaptor complexes medium subunits family. The AP-3 complex plays a role in protein trafficking to lysosomes and specialized organelles.

Gene Name: Adaptor-related protein complex 3, mu 2 subunit

Alternative Symbols: P47B, AP47B, CLA20

Protein Name: AP-3 complex subunit mu-2

Molecular Weight: 47kDa

Gene ID: 10947

NCBI Accession: NP_006794

UniProt: P53677