Homeobox A11 (HOXA11) antibody

Antigen: Homeobox A11 (HOXA11)

Synonyms: HOX1, HOX1I, Hox-1.9, Hoxa-11, HOXA11, GHOX1I

Clonality: Polyclonal

Host: Rabbit

Reactivity: Cow (Bovine), Human, Rat (Rattus), Mouse (Murine), Rabbit, Dog (Canine)

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Catalog no.: ABIN406665

Additional Information

Alternative name: HOXA11 / HOX1I

Gene ID: HOXA11

UniProt: P31270

Immunogen: The immunogen for anti-HOXA11 antibody: synthetic peptide directed towards the middle region of human HOXA11

Sequence: FETAYGTPENLASSDYPGDKSAEKGPPAATATSAAAAAAA TGAPATSSSD

Cross-Reactivity: Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rabbit, Rat (Rattus)

Format: Lyophilized

Reconstitution: Add 50 µl of distilled water. Final anti-HOXA11 antibody concentration is 1 mg/ml.

Description: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA11 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Characteristics: Antigen Size: 313 amino acids

Molecular Weight: 34kDa

Application Details

Application Notes: WB Suggested Anti-HOXA11 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Transfected 293T.

Purification: Affinity Purified

Buffer: PBS

Storage (Long Term): For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.

Storage (Short Term): Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.

Restrictions: For Research Use only

Images

WB Suggested Anti-HOXA11 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Transfected 293T

Publications

Product: Connell, Guess, Chen et al.: "HOXA11 is critical for development and maintenance of uterosacral ligaments and deficient in pelvic prolapse." in: The Journal of clinical investigation, Vol. 118, Issue 3, pp. 1050-5, 2008 (PubMed).