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Details for Product No. ABIN406684

ARP1 Actin-Related Protein 1 Homolog A, Centractin alpha (Yeast) (ACTR1A) (Middle Region) antibody

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Antigen
Synonyms ARP1, CTRN1, arp1, centractin, ctrn1, Arp1, alpha-Arp1, ACTR1A
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Mouse (Murine), Rat (Rattus), Dog (Canine), Xenopus laevis, Zebrafish (Danio rerio), Cow (Bovine), Human, Chicken
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN406684
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-ACTR1A antibody: synthetic peptide directed towards the middle region of human ACTR1A
Sequence AIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSR FRAPELLFRP
Predicted Reactivity African clawed frog : 100%, Bovine : 100%, Chicken : 100%, Horse : 100%, Human : 100%, Pig : 100%, Rabbit : 100%
Characteristics This is a rabbit polyclonal antibody against ACTR1A. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name ACTR1A
Background ACTR1A is a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
Molecular Weight 41kDa
Gene ID 10121
NCBI Accession NP_005727, NM_005736
UniProt P61163
Research Area Signaling, Cytoskeleton, Microfilaments
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-ACTR1A antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Sugarbaker, Richards, Gordon et al.: "Transcriptome sequencing of malignant pleural mesothelioma tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 9, pp. 3521-6, 2008 (PubMed).

Alternatives for antigen "ARP1 Actin-Related Protein 1 Homolog A, Centractin alpha (Yeast) (ACTR1A)", type "Antibodies"
Hosts (23), (4), (3)
Reactivities (27), (20), (17), (13), (12), (12)
Applications (18), (12), (10), (3), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (14), (2), (2), (2), (1), (1), (1), (1)
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