Transferrin Receptor antibody

Catalog No. ABIN452556

The Mouse Monoclonal anti-Transferrin Receptor antibody (Clone CY-TFR) (ABIN452556) specifically detects Transferrin Receptor in EIA. The antibody is reactive with Human samples.

Quick Overview for Transferrin Receptor antibody (ABIN452556)

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Transferrin Receptor antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: CY-TFR

Product Details anti-Transferrin Receptor Antibody

Specificity: Reactive with Human Transferrin Receptor/CD71

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: TfR1, p90, Transferrin receptor protein 1

Purification: Affinity Chromatography on Protein G.

Immunogen: Purified human Transferrin Receptor.

Isotype: IgG1

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2 without preservatives.

Preservative: Without preservative

Storage: -20 °C

Storage Comment: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Transferrin Receptor

Target: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Alternative Name: CD71 / TFRC

Background: The transferrin receptor has been structurally characterized as a sulfide bound dimer of identical glycoprotein subunits of 95 kDa. The transferrin receptor is not present on resting blood lymphocytes. On PBL, the receptor appears after activation. The expression of transferrin receptor is coordinately regulated with cell growth. Present on T and B cell lines. The soluble (or serum) transferrin receptor (sTfR) is a circulating truncated form of the membrane receptor protein, it is an 85 kDa glycoprotein forming in serum a 320 kDa complex with diferric transferrin. The most important clinical use of the sTfR determination is in the differential diagnosis between iron deficiency anaemia and the anaemia of chronic disease.Synonyms: TfR1, Transferrin receptor protein 1, p90

Gene ID: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis