Peroxiredoxin 1 antibody (Middle Region)

Catalog No. ABIN453291

The Rabbit Polyclonal anti-Peroxiredoxin 1 antibody (ABIN453291) specifically detects Peroxiredoxin 1 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for Peroxiredoxin 1 antibody (Middle Region) (ABIN453291)

Target: Peroxiredoxin 1 (PRDX1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Peroxiredoxin 1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Peroxiredoxin 1 Antibody

Binding Specificity: Middle Region

Specificity: This antibody reacts to Peroxiredoxin-1 (PRDX1).

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human PRDX1

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Peroxiredoxin 1

Target: Peroxiredoxin 1 (PRDX1)

Alternative Name: Peroxiredoxin-1 / PRDX1

Background: PRDX1 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. This protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression.Synonyms: NKEF-A, NKEFA PAGA, Natural killer cell-enhancing factor A, PAG, PAGB, PRDX-1, Proliferation-associated gene protein, Prx-1, Prx1, TDPX2, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2

Gene ID: 5052

NCBI Accession: NP_002565

UniProt: Q06830

Pathways: p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events